Hans-Christoph Pape Selected Research

Multiple Trauma (Multiple Injuries)

7/2022	Occult hypoperfusion and changes of systemic lipid levels after severe trauma: an analysis in a standardized porcine polytrauma model.
1/2022	Effects of Occult Hypoperfusion on Local Circulation and Inflammation - An Analysis in a Standardized Polytrauma Model.
3/2021	Splenectomy is associated with altered leukocyte kinetics after severe trauma.
1/2021	Damage control orthopaedics in polytraumatized patients- current concepts.
12/2020	Reaming of femoral fractures with different reaming irrigator aspirator systems shows distinct effects on cardiac function after experimental polytrauma.
11/2020	Fracture fixation strategy and specific muscle tissue availability of neutrophilic granulocytes following mono- and polytrauma: intramedullary nailing vs. external fixation of femoral fractures.
10/2020	Altered cell surface receptor dynamics and circulatory occurrence of neutrophils in a small animal fracture model.
1/2020	How to detect a polytrauma patient at risk of complications: A validation and database analysis of four published scales.
1/2020	Structural alterations and inflammation in the heart after multiple trauma followed by reamed versus non-reamed femoral nailing.
1/2020	Cardiac Glucose and Fatty Acid Transport After Experimental Mono- and Polytrauma.

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Hans-Christoph Pape Research Topics

Disease

74	Wounds and Injuries (Trauma) 07/2022 - 03/2002
28	Multiple Trauma (Multiple Injuries) 07/2022 - 06/2002
21	Hemorrhagic Shock 12/2020 - 07/2002
18	Inflammation (Inflammations) 01/2022 - 10/2003
17	Sepsis (Septicemia) 11/2021 - 11/2002
17	Hemorrhage 01/2020 - 07/2002
12	Infections 01/2022 - 03/2004
12	Shock 01/2022 - 11/2002
10	Multiple Organ Failure (MODS) 01/2021 - 11/2004
10	Femoral Fractures (Femoral Fracture) 11/2020 - 10/2002
6	Disease Progression 03/2021 - 03/2005
6	Contusions 01/2021 - 04/2005
6	Lacerations 12/2020 - 06/2014
6	Acute Lung Injury 01/2020 - 09/2007
6	Pneumonia (Pneumonitis) 01/2019 - 09/2008
5	Soft Tissue Injuries (Soft Tissue Injury) 02/2022 - 06/2010
5	Open Fractures (Compound Fracture) 02/2022 - 02/2013
5	Pain (Aches) 10/2021 - 03/2004
5	Hypothermia 12/2014 - 03/2004
4	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2021 - 03/2007
4	Edema (Dropsy) 07/2008 - 09/2006
3	Humeral Fractures 12/2020 - 01/2015
3	Rupture 05/2019 - 03/2015
2	Periprosthetic Fractures 01/2022 - 06/2011
2	Femoral Neck Fractures 01/2022 - 12/2016
2	Compression Fractures (Compression Fracture) 10/2021 - 01/2018
2	Osteomyelitis 03/2021 - 09/2018
2	Myocardial Contusions 01/2020 - 02/2003
2	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2019 - 03/2002
2	Lung Injury 12/2017 - 06/2015
2	Cicatrix (Scar) 01/2017 - 03/2015
2	Congenital Abnormalities (Deformity) 01/2017 - 02/2005
2	Surgical Wound Infection 03/2015 - 02/2013
2	Shoulder Fractures 01/2015 - 07/2013
2	Ischemia 09/2011 - 08/2007
2	Thoracic Injuries (Chest Injury) 06/2010 - 02/2005
2	Hypersensitivity (Allergy) 03/2006 - 11/2002
1	Closed Fractures (Closed Fracture) 02/2022
1	Lactic Acidosis 01/2022

Drug/Important Bio-Agent (IBA)

19	CytokinesIBA 12/2020 - 10/2003
18	Interleukin-6 (Interleukin 6)IBA 11/2020 - 10/2003
13	Interleukin-10 (Interleukin 10)IBA 12/2017 - 07/2002
10	salicylhydroxamic acid (SHAM)IBA 01/2020 - 11/2002
9	Peroxidase (Myeloperoxidase)IBA 05/2014 - 09/2006
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2007 - 07/2002
5	Interleukin-8 (Interleukin 8)IBA 11/2020 - 02/2007
4	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2015
4	Anti-Bacterial Agents (Antibiotics)IBA 01/2020 - 06/2010
4	Dehydroepiandrosterone (DHEA)IBA 05/2014 - 07/2002
3	Ringer's LactateIBA 02/2013 - 07/2002
2	C-Reactive ProteinIBA 11/2021 - 01/2015
2	Troponin IIBA 01/2021 - 01/2020
2	Fatty Acid-Binding ProteinsIBA 01/2021 - 01/2021
2	Complement System Proteins (Complement)IBA 12/2020 - 01/2020
2	AcidsIBA 01/2020 - 01/2020
2	SolutionsIBA 05/2019 - 04/2011
2	Interleukin-18 (Interleukin 18)IBA 12/2017 - 09/2011
2	ElementsIBA 01/2017 - 04/2011
2	Lactic Acid (Lactate)FDA LinkGeneric 06/2015 - 11/2007
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 06/2013 - 11/2012
2	Toll-Like Receptors (Toll-Like Receptor)IBA 06/2013 - 12/2008
2	InterleukinsIBA 09/2011 - 06/2006
2	Hormones (Hormone)IBA 11/2007 - 07/2002
2	Biological ProductsIBA 09/2007 - 07/2004
2	SteroidsIBA 02/2007 - 07/2002
2	Flutamide (Eulexin)FDA LinkGeneric 11/2006 - 10/2006
2	4,4',4''- (4- propyl- ((1)H)- pyrazole- 1,3,5- triyl) tris-phenolIBA 09/2006 - 06/2006
2	Estrogen ReceptorsIBA 09/2006 - 06/2006
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 03/2006 - 03/2005
1	LipidsIBA 07/2022
1	CreatinineIBA 04/2022
1	hydroxide ionIBA 01/2022

Therapy/Procedure

19	Resuscitation 07/2022 - 07/2002
16	Fracture Fixation 03/2021 - 03/2002
13	Intramedullary Fracture Fixation 01/2021 - 11/2005
12	Length of Stay 01/2020 - 02/2006
9	Therapeutics 08/2021 - 10/2003
7	Critical Care (Surgical Intensive Care) 10/2018 - 02/2005
7	Punctures 08/2009 - 07/2002
6	Ligation 08/2009 - 11/2002
5	Arthroplasty 01/2022 - 06/2011
5	Laparotomy 01/2020 - 06/2006
5	Surgical Amputation (Amputations) 05/2011 - 01/2004
4	Operative Surgical Procedures 06/2019 - 10/2002
4	Orthopedic Procedures 01/2015 - 06/2002
4	Induced Hypothermia 12/2014 - 03/2004
3	Negative-Pressure Wound Therapy 02/2022 - 12/2008
3	Osteotomy 12/2021 - 06/2004
3	External Fixators 09/2013 - 03/2004
2	Hemiarthroplasty 01/2022 - 01/2015
2	Operative Time 01/2022 - 02/2013
2	Kyphoplasty 10/2021 - 01/2018
2	Hip Replacement Arthroplasty (Total Hip Replacement) 01/2021 - 06/2004
2	Debridement 12/2013 - 02/2013
2	Fasciotomy 02/2013 - 05/2007
2	Mechanical Ventilators (Ventilator) 04/2012 - 02/2007
2	Thoracotomy 02/2008 - 04/2005
1	Skin Transplantation (Skin Grafting) 02/2022
1	Reoperation 02/2022
1	Resuscitation Orders (Do Not Resuscitate Orders) 01/2022